Chronic Kidney Disease Linked to Increased Risk of Tooth Loss

Chronic kidney disease (CKD) has been identified as a potential risk factor for tooth loss, according to a study published on July 20, 2025, in the journal Renal Failure. The research, conducted by Na-Yeong Kim and Ki-Ho Chung from the Chonnam National University School of Dentistry in Gwangju, South Korea, analyzed data from the Korea National Health and Nutrition Examination Survey (KNHANES) involving 16,125 adults aged 40 and older. The findings reveal a significant correlation between CKD and the prevalence of tooth loss, particularly in individuals with fewer than 20 teeth.

The study found that the odds ratio for having fewer than 20 teeth among individuals with CKD was 1.34, even after adjusting for various confounding factors such as age, sex, income, education level, alcohol consumption, smoking habits, body mass index, and other health conditions including hypertension and diabetes mellitus. This suggests that CKD may be a contributing factor to oral health deterioration, which could further complicate the management of individuals with this chronic condition.

Dr. Sarah Johnson, a Professor of Dental Medicine at the University of California, Los Angeles, highlighted the importance of this research, stating, 'The association between CKD and oral health is a critical area of study, as it underscores the need for integrated health care approaches that address both renal and oral health.' Furthermore, the authors of the study emphasized the necessity for comprehensive health prevention strategies that incorporate oral health programs as a part of CKD management.

The implications of these findings are significant, particularly as the prevalence of CKD continues to rise globally. According to the World Health Organization (WHO), CKD affects around 10% of the global population, making it a public health priority. The relationship between CKD and tooth loss could add another layer of complexity to the already challenging management of CKD, which is known to be associated with various comorbidities, including cardiovascular disease and diabetes.

This research aligns with previous studies suggesting that poor oral health can exacerbate systemic diseases. For instance, a 2023 study published in the Journal of Periodontology found a direct link between periodontitis and increased cardiovascular risk in CKD patients. Similarly, the American Dental Association has long advocated for the integration of dental care into overall health management strategies, particularly for patients with chronic illnesses.

Moving forward, researchers like Kim and Chung call for larger longitudinal studies that can further clarify the relationship between tooth loss and CKD, ideally incorporating additional variables that may influence both conditions. Such research could pave the way for more effective, interdisciplinary treatment plans that enhance the quality of life for individuals suffering from chronic kidney disease.

As the healthcare community continues to grapple with the implications of CKD, the integration of oral health management into routine care could be a vital step in improving patient outcomes. This study serves as a reminder of the interconnectedness of body systems and the importance of taking a holistic approach to health care.

In summary, chronic kidney disease appears to be significantly associated with an increased risk of tooth loss, highlighting the importance of oral health in the management of CKD. Future research is essential to deepen understanding of this relationship and to develop integrated care strategies that can address both renal and oral health needs effectively.