Discovery of Oldest Human DNA Sheds Light on Ancient Ancestry

June 12, 2025
Discovery of Oldest Human DNA Sheds Light on Ancient Ancestry

In a groundbreaking study published in the journal Nature, researchers have sequenced the oldest high-quality human DNA ever recovered, revealing intricate details about a lost branch of the human family tree. This DNA, dating back approximately 45,000 years, was found in a cave in Germany called Ranis, where scientists unearthed fragments belonging to at least six individuals, including men, women, and infants. This discovery provides critical insights into the lives of early modern humans who coexisted with Neanderthals, a species they encountered upon migrating into Europe from the southeast.

The Ranis cave, significant for its archaeological findings, has long been a subject of interest regarding the makers of Lincombian-Ranisian-Jerzmanowician (LRJ) tools, which were previously attributed to either Neanderthals or modern humans. The latest genetic analysis confirms that these tools were indeed crafted by modern humans, establishing a connection between the inhabitants of Ranis and a contemporary skull found in Zlatý kůň, Czechia. According to Dr. Johannes Krause, senior author of the study and a researcher at the Max Planck Institute for Evolutionary Anthropology, the genetic linkage indicates these individuals were part of an extended community rather than isolated wanderers.

The research team conducted DNA extraction and analysis from the remains found in both sites, revealing that the woman from Zlatý kůň and two individuals from Ranis were fifth- or sixth-degree relatives. This finding suggests a broader social structure among the early European populations, as they shared genetic material across distances. The group size was estimated to be only a few hundred individuals, highlighting the precarious existence of early humans in a hostile Ice Age environment, where they faced competition from established Neanderthal populations.

Interestingly, despite their contributions to the genetic tapestry of modern humans, the Ranis and Zlatý kůň groups appear to have left no direct descendants; their genetic lineage became extinct. The DNA analysis indicated that their connection to Neanderthals was rooted in an ancestral encounter from 45,000 to 49,000 years ago, rather than from recent interbreeding.

The appearance of these early modern humans, inferred from genetic data, suggested they had dark skin, dark hair, and brown eyes, consistent with their recent African origins. This research not only enhances our understanding of migration patterns but also underscores the complexities of human evolution and adaptation in ancient Europe.

The implications of this study extend beyond mere ancestry. It prompts a reevaluation of how we perceive human migration and interaction with other hominins. As Dr. Krause aptly stated, this research provides deeper insights into the earliest pioneers who settled in Europe, shedding light on a chapter of human history that was previously shrouded in mystery. The findings challenge existing narratives about the interactions between modern humans and Neanderthals, suggesting that the past is more nuanced than previously thought. As scientists continue to explore these ancient lineages, we gain not only knowledge about our origins but also a deeper understanding of the survival and adaptation strategies of our ancestors.

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oldest human DNAancient ancestryNeanderthalsmodern humansMax Planck InstituteRanis caveZlatý kůňhuman evolutiongenetic analysisarchaeological discoveryIce Age Europemigration patternsearly human communitiesLincombian-Ranisian-Jerzmanowician toolshuman family treeextinction of lineagesgenetic lineagepaleoanthropologyancient human remainsfossil discoveriesarchaeological evidencehuman migrationmodern human traitsevolutionary anthropologyscientific researchhistorical contextgenetic heritageancient human populationssoutheast migration

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